Longest UN climate talks end
Marathon international climate talks ended on 15 December 2019 with negotiators postponing until next year a key decision on how to regulate global carbon markets.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22345-longest-un-climate-talks-end.html
#COP25 #LongestUN #climatetalks #Madrid #Glasgow #greenhousegas
India in CCPI 2020
India is among the top 10 nations as per the Climate Change Performance Index (CCPI) which is based parameters like renewable power and energy use efficiency, Power Minster R K Singh said.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22344-india-in-ccpi-2020.html
#CCPI2020 #India #RKSingh #COP #NDCs #CCPI
Khyber Pass economic agreement
Pakistan and the World Bank has signed a project agreement worth $406.6 million for financing the Khyber Pass Economic Corridor (KPEC) project with an aim to promote economic development.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22343-khyber-pass-economic-agreement.html
#Khyber #KPEC #WorldBank #Pakistan
MCA's 2019 Review
In its year-end review, the Ministry of Corporate Affairs (MCA) on 15 December 2019 mentioned the various steps it undertook in 2019 for ease of doing business and creating a robust insolvency framework.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22342-mca-s-2019-review.html
#MCA #SPICe #NCLT #CCI #DVRs #WorldBank #GreenChannel #Amendment
Draft guidelines to treat rare genetic diseases
In a bid to attract the pharmaceutical industry for pooling investments in drugs for treating rare diseases, country’s apex research body Indian Council of Medical Research (ICMR) has come up with national guidelines for gene therapy related clinical trials.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22341-draft-guidelines-to-treat-rare-genetic-diseases.html
#ICMR #PID #CDSCO #NDCTR #India #CAGR #orphandrug
Marathon international climate talks ended on 15 December 2019 with negotiators postponing until next year a key decision on how to regulate global carbon markets.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22345-longest-un-climate-talks-end.html
#COP25 #LongestUN #climatetalks #Madrid #Glasgow #greenhousegas
India in CCPI 2020
India is among the top 10 nations as per the Climate Change Performance Index (CCPI) which is based parameters like renewable power and energy use efficiency, Power Minster R K Singh said.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22344-india-in-ccpi-2020.html
#CCPI2020 #India #RKSingh #COP #NDCs #CCPI
Khyber Pass economic agreement
Pakistan and the World Bank has signed a project agreement worth $406.6 million for financing the Khyber Pass Economic Corridor (KPEC) project with an aim to promote economic development.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22343-khyber-pass-economic-agreement.html
#Khyber #KPEC #WorldBank #Pakistan
MCA's 2019 Review
In its year-end review, the Ministry of Corporate Affairs (MCA) on 15 December 2019 mentioned the various steps it undertook in 2019 for ease of doing business and creating a robust insolvency framework.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22342-mca-s-2019-review.html
#MCA #SPICe #NCLT #CCI #DVRs #WorldBank #GreenChannel #Amendment
Draft guidelines to treat rare genetic diseases
In a bid to attract the pharmaceutical industry for pooling investments in drugs for treating rare diseases, country’s apex research body Indian Council of Medical Research (ICMR) has come up with national guidelines for gene therapy related clinical trials.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/22341-draft-guidelines-to-treat-rare-genetic-diseases.html
#ICMR #PID #CDSCO #NDCTR #India #CAGR #orphandrug
Ksgindia
Longest UN climate talks end | KSG India | Khan Study Group
Marathon international climate talks ended on 15 December 2019 with negotiators postponing until next year a key decision on how to regulate global carbon markets. After two weeks of negotiations in
ICMR sero-survey
India could be witnessing a much wider spread of coronavirus infections and the rate of contagion may be a lot higher in most-affected cities such as Delhi, Mumbai, and Pune,
https://www.ksgindia.com/study-material/news-for-aspirants/23925-icmr-sero-survey.html
#icmr #survey #covid19
India could be witnessing a much wider spread of coronavirus infections and the rate of contagion may be a lot higher in most-affected cities such as Delhi, Mumbai, and Pune,
https://www.ksgindia.com/study-material/news-for-aspirants/23925-icmr-sero-survey.html
#icmr #survey #covid19
Biobank of samples for research
The task force set up by the Indian Council of Medical Research (ICMR) has recommended launching a biobank or repository of test samples to understand clinical patterns in coronavirus cases, expedite test kit validation, and study the immune response to the virus.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/24010-biobank-of-samples-for-research.html
#Biobank #ICMR #coronavirus #PPEfabric #DBT #diagnostictestkits
The task force set up by the Indian Council of Medical Research (ICMR) has recommended launching a biobank or repository of test samples to understand clinical patterns in coronavirus cases, expedite test kit validation, and study the immune response to the virus.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/24010-biobank-of-samples-for-research.html
#Biobank #ICMR #coronavirus #PPEfabric #DBT #diagnostictestkits
Ksgindia
Biobank of samples for research | KSG India | Khan Study Group
The task force set up by the Indian Council of Medical Research (ICMR) has recommended launching a biobank or repository of test samples to understand clinical patterns in coronavirus cases, expedite
ICMR's 2nd sero-survey
The ICMR's second sero-survey shows that Indian population is still far from achieving herd immunity against coronavirus infection
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/26094-icmr-s-2nd-sero-survey.html
#ICMR #SeroSurvey #COVID19 #Coronavirus #UPSCOnlineClasses #OnlineClassses #IASOnlineclasse
The ICMR's second sero-survey shows that Indian population is still far from achieving herd immunity against coronavirus infection
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/26094-icmr-s-2nd-sero-survey.html
#ICMR #SeroSurvey #COVID19 #Coronavirus #UPSCOnlineClasses #OnlineClassses #IASOnlineclasse
Ksgindia
ICMR's 2nd sero-survey | KSG India | Khan Study Group | Best IAS Coaching Preparation Institute Online
The ICMR's second sero-survey shows that Indian population is still far from achieving herd immunity against coronavirus infection, Union health minister Harsh Vardhan said on 27 September 2020 while
Potential treatment for COVID-19
The ICMR in collaboration with a Hyderabad-based biopharmaceutical company has developed “highly purified antisera” prepared by injecting inactivated SARS-CoV2 in horses, which can be a potential treatment for COVID-19.
Read More: https://ksgindia.com/study-material/news-for-aspirants/26263-potential-treatment-for-covid-19.html
#COVID19 #ICMR #Potentialtreatment #UPSCOnlineClasses #OnlineClassses #IASOnlineclasses
The ICMR in collaboration with a Hyderabad-based biopharmaceutical company has developed “highly purified antisera” prepared by injecting inactivated SARS-CoV2 in horses, which can be a potential treatment for COVID-19.
Read More: https://ksgindia.com/study-material/news-for-aspirants/26263-potential-treatment-for-covid-19.html
#COVID19 #ICMR #Potentialtreatment #UPSCOnlineClasses #OnlineClassses #IASOnlineclasses
Ksgindia
Potential treatment for COVID-19 | KSG India | Khan Study Group | Best IAS Coaching Preparation Institute Online
The ICMR in collaboration with a Hyderabad-based biopharmaceutical company has developed “highly purified antisera” prepared by injecting inactivated SARS-CoV2 in horses, which can be a potential
Advisory on CRISPR SARS CoV-2 test
The Indian Council of Medical Research (ICMR) has issued an advisory for the use of indigenously developed Feluda paper strip test, which is based on CRISPR-Cas9 technology for diagnosis of SARS-CoV-2, by laboratories.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/26730-advisory-on-crispr-sars-cov-2-test.html
#CRISPR #SARS #CoV2test #ICMR #UPSCOnlineClasses #OnlineClassses #IASOnlineclasses
The Indian Council of Medical Research (ICMR) has issued an advisory for the use of indigenously developed Feluda paper strip test, which is based on CRISPR-Cas9 technology for diagnosis of SARS-CoV-2, by laboratories.
Read More: https://www.ksgindia.com/study-material/news-for-aspirants/26730-advisory-on-crispr-sars-cov-2-test.html
#CRISPR #SARS #CoV2test #ICMR #UPSCOnlineClasses #OnlineClassses #IASOnlineclasses
Ksgindia
Advisory on CRISPR SARS CoV-2 test | KSG India | Khan Study Group | Best IAS Coaching Preparation Institute Online
The Indian Council of Medical Research (ICMR) has issued an advisory for the use of indigenously developed Feluda paper strip test, which is based on CRISPR-Cas9 technology for diagnosis of SARS-CoV-
Today's Headlines - 18 August 2023
IITG produces pluripotent stem cells
GS Paper - 3 (Biotechnology)
Researchers from the Indian Institute of Technology Guwahati (IITG) in collaboration with scientists from Christian Medical College, Vellore, have reported a method to convert regular human skin cells into pluripotent stem cells. The human body is made of many kinds of cells – nerve cells, heart cells, liver cells, pancreatic cells, and so on, with unique structures and functions.
More about the News
All these distinctive cells originate from stem cells to perform a specific function. Lack of any of this cell type in a human body will result in a disease or disorder.
Thus, stem cells can be programmed to develop into mature functional cells, which can be used to replace damaged cells.
Stem Cells have to be extracted from embryos or parts of the adult human body like the brain or bone marrow, which is challenging from both ethical and practical aspects.
Thus, scientists are exploring techniques to convert ordinary cells, like skin or blood cells, into pluripotent stem cells – stem cells that can be programmed to develop into any other form of an adult cell type. These cells are called Induced Pluripotent Stem Cells (iPSCs).
The most important advantage of iPSCs is their potential to produce patient-specific cells which can be transplanted to the site of injury or the site of tissue degeneration due to various disease conditions, and thereby, eliminate any chance of immune rejection.
The conversion of mature cells into iPSCs was first shown by Prof. Shinya Yamanaka, who won the Nobel Prize in 2012 for his discovery.
How it Prepared
This research involved introducing specific genes into mature cells to convert them into iPSCs.
The researchers have used a safe, integration-free method, and have introduced genes such as OCT3/4, SOX2, KLF4, L-MYC, LIN28 and a p53 shRNA into skin cells to transform them into iPSCs.
The iPSCs produced by the IITG and CMC researchers were versatile, maintained their genetic makeup well, and could potentially differentiate into a range of body cell types.
Additionally, tests confirmed that the DNA structure of the cells was not altered and matched that of the original cells. Importantly, these iPSCs were found to be free from bacterial contamination.
iPSCs are useful for the design of stem-cell therapies for a range of ailments. iPSCs can be programmed to become beta islet cells to treat diabetes, blood cells to treat leukaemia, or neurons to treat disorders like Parkinson's and Alzheimer’s diseases.
Given the importance and potential of stem cells, the Government of India actively supports stem cell research through the Department of Health Research-Indian Council of Medical Research (DHR-ICMR).
This commitment spans two decades and includes initiatives such as advanced research centres, thematic task forces, and iPSC generation.
The collaboration between IIT Guwahati and CMC Vellore aligns seamlessly with these efforts and India’s endeavour to be at the forefront of stem cell research.
#upsc #news #headline #IITG #pluripotent #stem #cells #biotechnology #technology #guwahati #biotechnology #christian #medical #college #vellore #human #pluripotent #nervecells #pancreaticcells #unique #functions #disease #adult #practical #IPSC #shinyayamanaka #nobelprize #parkinson #alzheimer #diabetes #forces #research #DHR #ICMR #department #taskforces #india
IITG produces pluripotent stem cells
GS Paper - 3 (Biotechnology)
Researchers from the Indian Institute of Technology Guwahati (IITG) in collaboration with scientists from Christian Medical College, Vellore, have reported a method to convert regular human skin cells into pluripotent stem cells. The human body is made of many kinds of cells – nerve cells, heart cells, liver cells, pancreatic cells, and so on, with unique structures and functions.
More about the News
All these distinctive cells originate from stem cells to perform a specific function. Lack of any of this cell type in a human body will result in a disease or disorder.
Thus, stem cells can be programmed to develop into mature functional cells, which can be used to replace damaged cells.
Stem Cells have to be extracted from embryos or parts of the adult human body like the brain or bone marrow, which is challenging from both ethical and practical aspects.
Thus, scientists are exploring techniques to convert ordinary cells, like skin or blood cells, into pluripotent stem cells – stem cells that can be programmed to develop into any other form of an adult cell type. These cells are called Induced Pluripotent Stem Cells (iPSCs).
The most important advantage of iPSCs is their potential to produce patient-specific cells which can be transplanted to the site of injury or the site of tissue degeneration due to various disease conditions, and thereby, eliminate any chance of immune rejection.
The conversion of mature cells into iPSCs was first shown by Prof. Shinya Yamanaka, who won the Nobel Prize in 2012 for his discovery.
How it Prepared
This research involved introducing specific genes into mature cells to convert them into iPSCs.
The researchers have used a safe, integration-free method, and have introduced genes such as OCT3/4, SOX2, KLF4, L-MYC, LIN28 and a p53 shRNA into skin cells to transform them into iPSCs.
The iPSCs produced by the IITG and CMC researchers were versatile, maintained their genetic makeup well, and could potentially differentiate into a range of body cell types.
Additionally, tests confirmed that the DNA structure of the cells was not altered and matched that of the original cells. Importantly, these iPSCs were found to be free from bacterial contamination.
iPSCs are useful for the design of stem-cell therapies for a range of ailments. iPSCs can be programmed to become beta islet cells to treat diabetes, blood cells to treat leukaemia, or neurons to treat disorders like Parkinson's and Alzheimer’s diseases.
Given the importance and potential of stem cells, the Government of India actively supports stem cell research through the Department of Health Research-Indian Council of Medical Research (DHR-ICMR).
This commitment spans two decades and includes initiatives such as advanced research centres, thematic task forces, and iPSC generation.
The collaboration between IIT Guwahati and CMC Vellore aligns seamlessly with these efforts and India’s endeavour to be at the forefront of stem cell research.
#upsc #news #headline #IITG #pluripotent #stem #cells #biotechnology #technology #guwahati #biotechnology #christian #medical #college #vellore #human #pluripotent #nervecells #pancreaticcells #unique #functions #disease #adult #practical #IPSC #shinyayamanaka #nobelprize #parkinson #alzheimer #diabetes #forces #research #DHR #ICMR #department #taskforces #india