ИБХФ РАН. Новости
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Новостной канал Федерального государственного бюджетного учреждения науки Института биохимической физики им. Н.М. Эмануэля Российской академии наук

Официальный сайт ИБХФ РАН: https://biochemphysics.ru/

Предложить новость: @A_V_Bychkova
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Access insights into the complex tumor microenvironment (TME) and gain a greater understanding of the role of heterogeneity in immune checkpoint responses. This virtual seminar will provide a useful tool for comprehensive analyses of immune cells in the TME.

🗓 27 April, 3:00 pm PST
🗓 28 April, 7:00 am JST

Key topics:
▪️ Application of tissue and tumor dissociation and preservation of research tissue samples.
▪️ Biomarker prediction and resistant mechanisms in PD-1 blockade.
▪️ Best practices to design and analyze immune cells in the TME.

➡️ REGISTER

#Wiley #Webinar #вебинар #обучение
Everyday Cell Culture Practice – Improve Reproducibility

🗓 Thursday, May 6, 2021
7 am PDT, 10 am EDT, 4 pm CEST
🧑‍💻 live or recorded

Key topics:
▪️ Effects of passage numbers
▪️ Correct use of FBS
▪️ Get to know your cells. Documentation and monitoring
▪️ Cell line authentication methods
▪️ Mycoplasma test methods

🌐 REGISTER

#webinar #eppendorf #обучение #вебинар
Five major steps in drug discovery

🗓 Wed, May 12, 2021

12:00 PM - 1:00 PM MSK

In this free webinar you will learn about:
💊 How to extract, concentrate, purify, formulate and characterize molecules
💊 Tips for achieving quick, reliable purifications with flash chromatography
💊 How to optimize ingredient formulation with spray drying and microencapsulation
💊 Case study I: How to synthesize or extract GlabrescionB
💊 Case study II: How to spray dry roselle

#webinar #вебинар #обучение #BUCHI
DATE: May 19th 2021
TIME: 10:00 CET

In this webinar you will learn:
How to image multiple fluorescent probes In Vivo with the removal of background fluorescence using Spectral Unmixing Technology;
Gather insight into imaging multiple cell types in the same animal using Bioluminescence;
Novel luciferases and luciferin mutants and how they have been used to image multiple cell types in the same animal.

#обучение #вебинар #webinar #PerkinElmer
🗓 Tuesday, May 18, 2021
10:00 am - 11:00 am

🧑‍💻 Online webinar

Join this webinar with Associate Professor Kristin Sainani to learn the steps of a complete data analysis, using real data on mental health in athletes. She will give practical, hands-on tips for how to approach each step of the analysis and how to improve rigor and reproducibility of your research.

You Will Learn:
What steps are needed for an effective data analysis
The importance of cleaning, checking, understanding, and plotting data
How to improve the rigor and reproducibility of your research

#вебинар #обучение #webinar #Stanford
The power of ONE: Immunology in the age of single-cell genomics

🗓 May 25, 2021
6 AM PDT, 9 AM EDT, 2 PM BST, 4 PM IDT

Key Learnings:

How single-cell genomics holds the potential to revolutionize the way we characterize complex immune cell assemblies and study their spatial organization, dynamics, clonal distribution, pathways and crosstalk
Learn how recent single-cell genomic studies are changing our perspective of various immune-related pathologies from cancer to autoimmune disease and neurodegeneration
Learn about recent and forthcoming technological and analytical advances in single-cell genomics and their huge potential impact on the future of immunology research and immunotherapy

➡️ REGISTER

#обучение #вебинар #webinar #CurrentProtocols
Live Webinar: Enhancing the Predictability of Preclinical Development

DATE: May 26, 2021
TIME: 8AM PST, 11 AM EST, 4 PM BST, 5PM CEST

Preclinical studies enable evaluation of drug candidates for both efficacy and safety within biological model systems. Physiological relevance of the models used can closely mimic the biochemical pathways, metabolism, and physiology of humans. Hence, primary cells, 3D cell culture / tissues, and cell-based assays comprise relevant model systems.

How to evaluate models to establish robust and reliable preclinical investigation of drug candidates prior to entering clinical trials
How to gain an understanding of the advancements in preclinical model systems and assays
What to consider from the latest innovations and impact on bioanalytical assays.

➡️ REGISTER

#обучение #вебинар #webinar #PerkinElmer
DATE: 26 May 2021
TIME: 10:00 AM ET | 4 PM CET

Drug development faces a significant challenge in that only 1 in 10 candidates make it to the market, often due to safety/toxicity issues rather than efficacy. Adoption of early assessments to de-risk drug candidates by identifying and de-prioritizing those with potential safety issues is of paramount importance.
Join this live
webinar where Dr. Peterson will discuss how in vivo fluorescence probes and strategies can be used in early drug screening.

Overview of the range of animal models and therapeutic areas supported by fluorescent imaging and imaging probes
Liver safety/toxicology imaging of the effects of chemical agents
Characterization of kidney safety/toxicology of Cyclosporin A and Rapamycin
Live Q & A

➡️ REGISTER

#вебинар #обучение #Webinar #PerkinElmer
Chromatography Virtual Academy: Flash cartridges, prep HPLC columns & co.

May 26th from 11:00 to 12:00 CEST


In this free webinar, gain valuable information on handling and use of chromatography consumables.
Ensure you are making the correct choices for your application from the wide selection of chromatography cartridges and columns available.


In the second part of our 4-part chromatography lecture series, join our purification specialist, Dr. Birke Götz in learning about:
✔️ Benefits and limitations of using flash cartridges, glass columns and prep HPLC columns
✔️ Equilibration, cleaning and storage of flash cartridges and prep HPLC columns
✔️ Dry and slurry packing of glass columns
✔️ Solid sample loading for flash applications
✔️ Liquid sample loading for flash and prep HPLC applications

🌐 REGISTER

#обучение #вебинар #Webinar #Buchi
Watch on demand: Characterising cancer cell states using spatial transcriptomics

Intratumor heterogeneity is a recognized cause of cancer treatment failure. While much of tumor heterogeneity is genetic in nature, recent work using single-cell RNA-Seq has detected a hitherto underappreciated level of transcriptional heterogeneity, leading to the notion of cancer cell states. Studies in melanoma, glioblastoma, and head and neck cancer among others have identified sets of cancer cell states, many of which relate to processes specific to the cell of origin.

Join this virtual seminar to:
Learn about how single-cell RNA-Seq and Spatial Transcriptomics can be integrated
Understand how cell states can be defined using gene modules
Explore how cancer cell states may be related to the tumor microenvironment
Consider the conservation of cancer cell states across diverse cancer types

➡️ Watch

#обучение #вебинар #webinar #CurrentProtocols
Высокоэффективная тонкослойная хроматография и ее место в современной лаборатории

🗓 26.05.21
11:00 (Мск)


▪️ ВЭТСХ пластины
▪️ Области применения с примерами
▪️ Автоматические приборы и современное ПО, архитектура ПО visionCATS
▪️ Комбинирование ВЭТСХ с различными методами детектирования:
описание вариантов комбинирования ▪️ ВЭТСХ с различными спектральными методами, а также методами биодетекции, включая тесты с бактериями, дрожжами, ферментами.

Подарки и бонусы онлайн-лектория Диаэм:
1⃣ Зарегистрированный участник вебинара получает скидку в 10% до конца года по любым позициям из презентации без ограничения в их количестве
2⃣ Слушатели, ответившие на вопросы анкеты, прилагаемой к материалам вебинара (рассылка по его окончанию) получают на выбор:
✔️ Любой набор diaGene на 50 выделений.
✔️ Комплект (1000 шт.) пробирок типа Eppendorf на 1,5 мл.
✔️ Комплект (1000 шт.) пробирок типа Eppendorf на 2,0 мл.

🌐 Подробнее

#обучение #вебинар #Webinar #Диаэм
Catch-up on-demand!

Listen to Dr. Omer Bayraktar of the Wellcome Sanger Institute as he introduces Cell2location, a novel platform for integrating single cell and spatial transcriptomics data.

What you will learn:
▪️ How Cell2location utilizes Bayesian modeling methods to combine single cell RNA-sequencing (scRNA-seq) information with spatial transcriptomic data
▪️ How it creates high-resolution tissue atlases, facilitating a greater understanding of gene expression across cell types present in complex tissues

➡️ Watch

#обучение #вебинар #Webinar #CurrentProtocols
Catch-up on demand

Mass cytometry has emerged in recent years as a powerful tool for single-cell analysis in both basic and clinical research studies.

📍 Michelle Poulin, Manager of North American Field Applications at Fluidigm, will provide a brief introduction of mass cytometry including a technical description of the core technology, cytometry by time-of-flight (used in CyTOF® systems), as well as an overview of the isotopic metal-labeled antibodies and panel kits that enable analysis of over 50 markers per cell.

In this virtual seminar you will learn how the Gaudilliere group is applying mass cytometry and other proteomic technologies to obtain multi-omic views of several clinical scenarios, including:
▪️ immune mechanisms of surgical recovery and complications
▪️ pregnancy and preterm birth
▪️ immune dysfunction and outcomes prediction in patients with COVID-19

🌐 REGISTER

#обучение #вебинар #Webinar #CurrentProtocols
Accelerating innovation for polymeric materials with molecular modelling

🗓 June 10, 2021
10am PDT / 1pm EDT / 6pm BST / 7pm CEST

Polymeric materials have found widespread applications across a diverse range of industries. Their development has traditionally relied on experimental exploration of candidate chemistries; which is time-consuming, expensive and limited in scope. As we push toward the next generation of polymers with enhanced performance and sustainability, computational chemistry and informatics provide a critical connection between chemistry and properties.

You will learn:
✔️ How polymer innovation and manufacturing use chemically informed simulations
✔️ Examples in bio-based polymers, thermoset resins, and thermoplastics such as polyacrylates and polyolefins
✔️ Techniques for integrating simulation into industrial research and development

➡️ REGISTER

#webcast #обучение #webinar #вебинар
Swaying the advantage: how the immune system can overcome tumor adaptability

The tumor microenvironment is a cellular niche composed of neoplastic and non-neoplastic cells. Components of the latter include hematopoetic (immune) cells that serve as sentinels that patrol most anatomical environments within the host and serve to alert and respond to perturbations in homeostasis. Meanwhile, tumors are fittingly adaptable to the patrolling and effector functions of hematopoetic cells, and via multiple cellular and molecular responses, can reduce their vulnerability to death and clearance by the immune system. As such, a scenario of "survival of the fittest" is established.

In this webinar will discuss various aspects of the cellular and molecular interactions between the immune system and tumors, with an eye on establishing an advantage to the immune system in its quest to support the survival of the host.

➡️ Watch On Demand

#обучение #вебинар #Webinar
DATE: 17 June 2021
TIME: 3 PM CET | 9 AM ET

📌 Micro computed tomography (microCT) imaging has emerged as a powerful tool for the longitudinal assessment of lung disease progression in animal models. This technology provides a non-invasive evaluation of both the morphometry and functionality of lungs, exploiting the inherent contrast between air and tissue.

Webinar Highlights:
🔹 Evaluating drug efficacy in lung fibrosis studies using the Quantum microCT system
🔹 Preclinical mouse model to mimic stereotactic body radiotherapy (SBRT) for lung cancer treatment
🔹 Characterization of radiation-induced lung lesions using microCT
🔹 Live Q & A

🌐 REGISTER

#обучение #вебинар #Webinar #PerkinElmer
Med platforms Matter: Material science for cancer diagnostics and treatment

🗓 June 23, 2021
12:00 pm EDT


With the continued rise of interdisciplinary approaches bridging life and physical sciences, researchers are using every toolkit available to tackle the most pressing health problems.

Med and Matter recognize that multiple driving technologies emerging in medicine are being developed on innovative and advanced materials platforms; these technologies exploit the behavior of novel materials and phenomena, including biocompatible chemistries and mechanics, adaptive structures, transport properties, photodynamics, and more. Simply put, the underlying platforms used for medicine matter.

📍 Here, we focus on materials-based solutions for potential cancer treatment, diagnostics, and the next generation of personalized medicine.

➡️ REGISTER

#обучение #вебинар #webinar #CellPress
Расписание вебинаров Web of Science и Clerivate на июнь

📚 Научная аналитика: Web of Science и InCites

1⃣ Дополнительные возможности поиска и анализа информации на платформе Web of Science
23 июня, 14:00 (мск); 24 июня, 10:00 (мск)
Поиск и анализ информации в специализированных базах данных и региональных указателях на платформе Web of Science. Возможности расширенного поиска/advanced search в Web of Science Core Collection, поиск по организации и научным направлениям. Составление поисковых запросов с помощью полей поиска и логических операторов. Поиск в пристатейной библиографии.

2⃣ Возможности аналитического инструмента InCites для анализа цитируемости
23 июня, 07:00 (мск); 24 июня, 14:00 (мск)
InCites - это аналитическая оболочка, позволяющая сопоставлять и визуализировать данные по цитируемости из базы данных Web of Science Core Collection. InCites также позволяет оперировать десятками дополнительных библиометрических показателей, многие из которых позволяют сопоставлять цитируемость публикаций, сделанных в разных предметных областях. Всё это позволяет проводить сопоставление авторов, организаций и целых стран, анализировать сильные стороны в наших исследованиях, а также находить зарождающиеся исследовательские тенденции. На вебинаре расскажут о том, как устроен интерфейс InCites и разберут ряд наиболее интересных примеров анализа организаций, стран, отдельных авторов, а также поиска прорывных научных тематик.

3⃣ Возможности EndNote для работы с библиографией
23 июня, 10:00 (мск); 24 июня, 07:00 (мск)
Процесс подготовки статьи для подачи в международный журнал. Требования журналов к публикации. Создание собственной библиографической базы данных с помощью EndNote Online. Сортировка записей, создание групп и управление доступом к ним. Использование шаблонов оформления библиографии. Использование модуля Cite-While-You-Write для Microsoft Word и создание списка литературы непосредственно при написании текста.

📚 Как работать с международныими научными журналами

1⃣ Основные требования к публикациям в международных журналах
28 июня, 09:00 (мск); 29 июня, 14:00 (мск); 30 июня, 11:00 (мск)
Ожидания редактора. Основные причины отказов в публикации. Работа с правками рецензентов. Структура научной статьи. Практические советы по написанию основных разделов. Отличительные черты академического английского языка. Составление аннотации. Написание заголовков. Выбор ключевых слов.

2⃣ Подготовка публикации: организация и редактура текста, работа редактора
28 июня, 11:00 (мск); 29 июня, 09:00 (мск); 30 июня, 14:00 (мск)
Основные принципы организации текста научной статьи; аргументация в англоязычной традиции; как редактировать текст на всех уровнях его организации; принципы авторедактирования; в чём заключается работа редактора.

3⃣ Web of Science Academy: почему важно учиться рецензированию
28 июня, 14:00 (мск); 29 июня, 11:00 (мск); 30 июня, 09:00 (мск)
Роль рецензирования в повышении качества научных исследований. Почему важно сотрудничать с международными журналами в качестве рецензента. Что опыт рецензирования даёт автору публикации. Где и как можно научится правилам и практике качественного научного рецензирования; возможности Web of Science Academy/Publons.

🌐 Общая страница регистрации

#Clarivate #WebofScience #вебинар #обучение #webinar
​​📌 Wednesday, September 29th from 11:00 to 12:00 CEST (с 12 до 13 Мск)

Chromatography Virtual Academy: How to develop your method

In this free webinar, learn how to develop the optimal flash chromatography or prep HPLC method for your samples. See how to test your conditions quickly and easily and how to upscale. In the third part of our 4-part chromatography lecture series, join our purification expert, Dr. Birke Götz and discover how to:

Analyze sample solubility
Select ideal stationary and mobile phases with help of retention factor values, the Snyder triangle and more
Upscale from TLC or analytical HPLC to flash or prep HPLC
Improve resolution based on selectivity, retention factor and column efficiency
Plus: ask your own question with a guaranteed answer


REGISTRATION 🌐

#Обучение #Webinar #Buchi #ИАОИБХФРАН
Diffraction in drug development

🗓 25 January 2022
10:30 - 11:30 Eastern Time [US & Canada]
🗣 Language: English

📌 Consequently, solid form and particle size distribution are critical material attributes that must be measured and controlled. X-ray diffraction and laser diffraction are used for this purpose. They provide complementary information on particle size and crystallo-chemical composition. 

In this webinar, we will discuss: 
🔹 the fundamental differences between X-ray diffraction and laser diffraction
🔹 the insights provided by these two techniques
🔹 guidance for method development for both XRD and LD particle sizing

✔️ Will also show how Malvern Panalytical and Concept Life Sciences can support these activities in your drug development workflows.

🌐 Register

#обучение #webinar