*May 18, 2022*
*The importance of aging in cancer research*
"Individuals aged 70 and older bear half of the cancer mortality burden (about 5 million deaths each year), with another 40% borne by 50-to-70-year-old individuals. As such cancer is considered an aging-related disease."
https://www.nature.com/articles/s43587-022-00231-x
*The importance of aging in cancer research*
"Individuals aged 70 and older bear half of the cancer mortality burden (about 5 million deaths each year), with another 40% borne by 50-to-70-year-old individuals. As such cancer is considered an aging-related disease."
https://www.nature.com/articles/s43587-022-00231-x
Nature
The importance of aging in cancer research
Nature Aging - Cancer is a disease of aging, but it is rarely studied in aged animal models and older adults are often insufficiently represented in cancer clinical trials. To further our...
*May 18, 2022*
"Many age-related diseases share a common feature: the mitochondria of cells begin to malfunction. While the cause is not known, Buck Institute scientists have discovered a new mechanism of how mitochondria start to go wrong, which opens new doors for researchers to explore how to begin to fix the problem."
https://www.buckinstitute.org/news/buck-scientist-uncovers-clues-to-aging-in-mitochondria/
"Many age-related diseases share a common feature: the mitochondria of cells begin to malfunction. While the cause is not known, Buck Institute scientists have discovered a new mechanism of how mitochondria start to go wrong, which opens new doors for researchers to explore how to begin to fix the problem."
https://www.buckinstitute.org/news/buck-scientist-uncovers-clues-to-aging-in-mitochondria/
BUCK
Buck Scientist Uncovers Clues to Aging in Mitochondria - BUCK
Understanding how the process starts can point to new directions in aging research
Misha Batin:
News of the fight against neurodegeneration.
There are 3 recent papers on this topic.
First. In Nature, a team of scientists from Stanford published a publication in which they describe the results of the world's first transfusion of cerebrospinal fluid (CSF) from young to old mice.
CSF is a version of plasma for the central nervous system. It is a mixture of essential ions and nutrients that washes the brain, nourishing and cleansing it.
As we know, during the aging process of mammals, the cerebrospinal fluid shows a deterioration in its function.
Which in turn affects the ability to learn and memory.
But, as Tony Wyss-Coray and colleagues showed, the introduction of young CSF to old animals normalized their memory. CSF from young mice increased the proliferation and differentiation of oligodendrocyte progenitor cells in the old hippocampus.
Also, the young CSF restored oligodendrogenesis in old mice.
Oligodendrocytes produce the myelin sheath of neurons, but this process noticeably worsens with age. Scientists were able to identify the protein responsible for stimulating oligodendrogenesis — fibroblast growth factor 17 (Fgf17)
It should be noted that the replacement of organs, tissues and functions acts as an alternative to the idea of repairing something in the body itself. It is possible that this direction will overtake the hills of aging
https://www.nature.com/articles/s41586-022-04722-0
News of the fight against neurodegeneration.
There are 3 recent papers on this topic.
First. In Nature, a team of scientists from Stanford published a publication in which they describe the results of the world's first transfusion of cerebrospinal fluid (CSF) from young to old mice.
CSF is a version of plasma for the central nervous system. It is a mixture of essential ions and nutrients that washes the brain, nourishing and cleansing it.
As we know, during the aging process of mammals, the cerebrospinal fluid shows a deterioration in its function.
Which in turn affects the ability to learn and memory.
But, as Tony Wyss-Coray and colleagues showed, the introduction of young CSF to old animals normalized their memory. CSF from young mice increased the proliferation and differentiation of oligodendrocyte progenitor cells in the old hippocampus.
Also, the young CSF restored oligodendrogenesis in old mice.
Oligodendrocytes produce the myelin sheath of neurons, but this process noticeably worsens with age. Scientists were able to identify the protein responsible for stimulating oligodendrogenesis — fibroblast growth factor 17 (Fgf17)
It should be noted that the replacement of organs, tissues and functions acts as an alternative to the idea of repairing something in the body itself. It is possible that this direction will overtake the hills of aging
https://www.nature.com/articles/s41586-022-04722-0
Nature
Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17
Nature - Fgf17 in young CSF boosts oligodendrocyte progenitor cell proliferation and differentiation in the aged hippocampus, improving memory function.
Database of aging related drugs: https://genomics.senescence.info/drugs/index.php
#GeorgeChurch #AgeReversal #GeneTherapies
Targeting A $2 Dose AGING REVERSAL Therapy For Everyone | Dr George Church Interview Clips https://www.youtube.com/watch?v=MvxIFKQ8hmw
Targeting A $2 Dose AGING REVERSAL Therapy For Everyone | Dr George Church Interview Clips https://www.youtube.com/watch?v=MvxIFKQ8hmw
YouTube
Targeting A $2 Dose AGING REVERSAL Therapy For Everyone | Dr George Church Interview Clips
Dr George Church talks about combination therapies for age reversal, recently published papers from his lab and expresses his wish on developing inexpensive gene therapies like vaccine that can be equitably distributed to human.
Dr George Church is the Robert…
Dr George Church is the Robert…
Colleagues, we have launched 4 NFT collections to highlight organ health & severe consequences due to top 20 severe diseases.
Would love your comments, suggestions & discussion. Collected funds will go to the scientific groups which work on the same problems. If you wish to be among the funds recipients, please direct message:
Digital Celebrities Severe Illness:
https://opensea.io/collection/digitalcelebritiessevereillness
Digital Politicians Severe Illness:
https://opensea.io/collection/digital-politicians-severe-illness
Digital Athletes Sever Illness:
https://opensea.io/collection/digital-athletes-severe-illness
Digital Organs:
https://opensea.io/collection/longevity-anti-aging-collection-track-early-live-l
Would love your comments, suggestions & discussion. Collected funds will go to the scientific groups which work on the same problems. If you wish to be among the funds recipients, please direct message:
Digital Celebrities Severe Illness:
https://opensea.io/collection/digitalcelebritiessevereillness
Digital Politicians Severe Illness:
https://opensea.io/collection/digital-politicians-severe-illness
Digital Athletes Sever Illness:
https://opensea.io/collection/digital-athletes-severe-illness
Digital Organs:
https://opensea.io/collection/longevity-anti-aging-collection-track-early-live-l
OpenSea
Digital Celebrities Severe Illness - Collection
Each day 115,000 people die prematurely. Even celebs can't resist diseases. With this collection, the main message to the humanity is to take close care about your health as early as possible and support fundamental research of top 20 severe diseases.
Though…
Though…
Jose Cordeiro:
As I have mentioned before, the Hevolution Foundation in the KSA is finally starting... https://www.technologyreview.com/2022/06/07/1053132/saudi-arabia-slow-aging-metformin
As I have mentioned before, the Hevolution Foundation in the KSA is finally starting... https://www.technologyreview.com/2022/06/07/1053132/saudi-arabia-slow-aging-metformin
MIT Technology Review
Saudi Arabia plans to spend $1 billion a year discovering treatments to slow aging
The oil kingdom fears that its population is aging at an accelerated rate and hopes to test drugs to reverse the problem. First up might be the diabetes drug metformin.
*If Aging is Not a Disease, Then Neither is Cancer!*
"For starters, when, in the entire history of human medicine, have we ever used the excuse that something is not a disease just because it is naturally occurring?"
https://www.regenerativemedicinedaily.com/if-aging-is-not-a-disease
"For starters, when, in the entire history of human medicine, have we ever used the excuse that something is not a disease just because it is naturally occurring?"
https://www.regenerativemedicinedaily.com/if-aging-is-not-a-disease
Regenerativemedicinedaily
If Aging is Not a Disease, Then Neither is Cancer!
Many people will swear to the life extending properties of coffee, be it saving them from keeling over from exhausting in the early hours of the morning or saving an annoying co-worker from the unbridled rage of someone who hasn’t yet acquired their caffeine…
https://forever-healthy.org/news/rejuvenation-startup-summit-premieres-october-14-15-2022-in-berlin/
Forever Healthy
Rejuvenation Startup Summit premieres October, 14-15, 2022 in Berlin | Forever Healthy
The Forever Healthy Foundation is pleased to announce the world's first Rejuvenation Startup Summit will be held October 14-15, 2022 in Berlin. The Rejuvenation Startup Summit is a vibrant networking event for rejuvenation startups, longevity investors, and…