*Jan 15, 2022*
*Relationship Between 5 Epigenetic Clocks, Telomere Length, and Functional Capacity Assessed in Older Adults: Cross-Sectional and Longitudinal Analyses*
"In conclusion, neither rLTL nor 7-CpG DNAmAA was able to predict impairment in the analyzed assessments over a ~7-year time course. Similarly, DNAmAA estimated from 5 epigenetic clocks was not a good cross-sectional marker of health deterioration either."
*Note:*
*rLTL* = relative Leukocyte Telomere Length
*DNAmAA* = DNA methylation age acceleration
https://academic.oup.com/biomedgerontology/article/77/9/1724/6473288
*Relationship Between 5 Epigenetic Clocks, Telomere Length, and Functional Capacity Assessed in Older Adults: Cross-Sectional and Longitudinal Analyses*
"In conclusion, neither rLTL nor 7-CpG DNAmAA was able to predict impairment in the analyzed assessments over a ~7-year time course. Similarly, DNAmAA estimated from 5 epigenetic clocks was not a good cross-sectional marker of health deterioration either."
*Note:*
*rLTL* = relative Leukocyte Telomere Length
*DNAmAA* = DNA methylation age acceleration
https://academic.oup.com/biomedgerontology/article/77/9/1724/6473288
OUP Academic
Relationship Between 5 Epigenetic Clocks, Telomere Length, and Functional Capacity Assessed in Older Adults: Cross-Sectional and…
Abstract. DNA methylation age acceleration (DNAmAA, derived from an epigenetic clock) and relative leukocyte telomere length (rLTL) are widely accepted biomarke
Good podcast on dogs as a model organism for studying aging
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy50cmFuc2lzdG9yLmZtL3RhbGtpbmctYmlvdGVjaA/episode/YzQ5NzQ1MzMtMjY2MC00NmI5LWIyOWMtZDQyYTc0NWMxNmVj?ep=14
https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy50cmFuc2lzdG9yLmZtL3RhbGtpbmctYmlvdGVjaA/episode/YzQ5NzQ1MzMtMjY2MC00NmI5LWIyOWMtZDQyYTc0NWMxNmVj?ep=14
Google Podcasts
Talking Biotech with Dr. Kevin Folta - Celine Halioua: Extending Health and Life, Starting with Dogs
Dogs are a recent species, and because of their close associations with humans have diverged into hundreds of breeds with specific behaviors, sizes and builds. There also is a great range in life expectancy and anticipated disease. Dogs therefore provide…
Longevity InTime Anti-Aging Digital Health Immortality Transhumanist Channel
https://www.lifespan.io/news/study-results-suggest-human-aging-can-be-reversed/
This adds to the above paper and explains the redox signalling element.
https://www.frontiersin.org/articles/10.3389/fimmu.2021.636072/full
https://www.frontiersin.org/articles/10.3389/fimmu.2021.636072/full
Frontiers
Metabolic Regulation of Thymic Epithelial Cell Function
The thymus is the primary site of T lymphocyte development, where mutually inductive signaling between lymphoid progenitors and thymic stromal cells directs the progenitors along a well-characterized program of differentiation. Although thymic stromal cells…
Dear Longevity members!
As some of you might know, that there is a humanitarian crisis going on in Russia, because of the assault on Ukraine.
So many Russians fight to leave a country prior potential lockdown.
Longevity InTime is doing its impact to try to save at least few asylum seekers lives and can offer few seats on Emirates flight on 27-th of September from Sankt Petersburg through Dubai to the most destinations. Please direct me for details
Take a good care!
As some of you might know, that there is a humanitarian crisis going on in Russia, because of the assault on Ukraine.
So many Russians fight to leave a country prior potential lockdown.
Longevity InTime is doing its impact to try to save at least few asylum seekers lives and can offer few seats on Emirates flight on 27-th of September from Sankt Petersburg through Dubai to the most destinations. Please direct me for details
Take a good care!
*Sept 19, 2022*
*Alzheimer’s might not be primarily a brain disease. A new theory suggests it’s an autoimmune condition.*
https://theconversation.com/alzheimers-might-not-be-primarily-a-brain-disease-a-new-theory-suggests-its-an-autoimmune-condition-189047
*Alzheimer’s might not be primarily a brain disease. A new theory suggests it’s an autoimmune condition.*
https://theconversation.com/alzheimers-might-not-be-primarily-a-brain-disease-a-new-theory-suggests-its-an-autoimmune-condition-189047
The Conversation
Alzheimer’s might not be primarily a brain disease. A new theory suggests it’s an autoimmune condition.
Alzheimer’s may not be primarily a disease of the brain. It may be a disorder of the immune system within the brain. Beta-amyloid may not be an abnormal protein, but part of the brain’s immune system.
A harsh critique from Charles Brenner to David Sinclair...
*Sep 26, 2022*
*A Science-Based Review of the World's Best-Selling Book on Aging*
https://www.sciencedirect.com/science/article/abs/pii/S0167494322002126
*Sep 26, 2022*
*A Science-Based Review of the World's Best-Selling Book on Aging*
https://www.sciencedirect.com/science/article/abs/pii/S0167494322002126
This isn't a scientific article as such, but it well written and documented.
*Sept 29, 2022*
*Could epigenetic reprogramming reverse aging?*
https://leaps.org/fountain-of-youth/particle-3
*Sept 29, 2022*
*Could epigenetic reprogramming reverse aging?*
https://leaps.org/fountain-of-youth/particle-3
leaps.org
Could epigenetic reprogramming reverse aging?
The road to de-differentiation, the process by which cells return to an earlier state, is not paved with roses; de-differentiate too much and you may cause pathology and even death.
Just a bit off our topics, but maybe not necessarily off … support Peace & Longevity:
https://collaborateforpeace.com/?fbclid=IwAR2g_EL4rz4qnTRUljLOobhSSKXXjkqpWUmc-m6DNhwnV02LPfPELBU6W4g
https://collaborateforpeace.com/?fbclid=IwAR2g_EL4rz4qnTRUljLOobhSSKXXjkqpWUmc-m6DNhwnV02LPfPELBU6W4g
Collaborate For Peace
CREATE TOGETHER.